Bill and Melinda Gates are doing it right. From 1990 to recently, the childhood mortality rate has been cut in half. Why? Cause they pay attention to the things that matter. What kills kids worldwide? Malaria - and they’re hard at work on a vaccine. No worries about phantom illnesses or the craze of the week. Instead, they’ve got a solid focus on the things that actually matter.

So what do they propose to keep things going? Again – rate limiting steps...

How Bill and Melinda Gates are making the most of their philanthropy. It's no coincidence that one of GiveWell's top-rated charities is the Against Malaria Foundation.

Rate-limiting steps is a concept with metaphoric value in lots of spheres in life.